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Ashwagandha 20% Extract

Enhances Virility*
Healthy Cell Support*
Stress & Anxiety Support*
Enhances Cognitive Function*
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Product Information

Withania somnifera (commonly known as ashwagandha) has been used widely in Indian Ayurvedic medicine for thousands of years.

What is Ashwagandha?

In Sanskrit, Ashwagandha means "the smell of a horse", indicating the strength of a stallion. It was traditionally used to help people support a healthy immune system [1]. Ashwagandha is usually referred to as winter cherry or Indian ginseng because of its energizing properties [2]. Somnifera (meaning "sleep-inducing" in Latin) has been recommended for a sound night's sleep for centuries. The Western world has started showing an interest in recent years as extracts of the Ashwagandha plant possess multiple therapeutic properties, especially rejuvenating properties. *

How could Ashwagandha Support My Health?

There is much scientific information supporting the powerful regenerative properties of ashwagandha (a "Rasayana" of Ayurveda). Ashwagandha is a common Indian household remedy. It is considered the best tonic for both old and young and is used by people as an aphrodisiac. It is one of the best nervine (used to calm the nerves) tonics of Ayurveda, the most ancient system of the medical world. *

Research suggests that Ashwagandha may support antioxidant activity, cortisol support, healthy cell production, joint support, blood support, healthy thyroid function and cardiovascular support. *

  • According to various surveys, work related stress and anxiety is one of the major causes of disease, ranging from psychiatric disorders to endocrine disorders. This includes diabetes mellitus, hypothyroidism, sexual dysfunction in males, peptic ulcers, hypertension, and ulcerative colitis [3]. The stress hormone, cortisol, can cause all sorts of health problems if left unchecked. Ashwagandha is touted as one of the best herbs for promoting a calm, relaxed mood because of it's adaptogenic qualities. Adaptogens are substances which help the body cope with environmental and internal stress and induces sleep. This concept in Ayurveda is known as "rejuvenation therapy" as it helps energize the body, strengthen our immunity, and balances our hormone levels. Regular intake of Ashwagandha with milk has been researched and suggests that new immune cells are activated, thus providing enough suggestion for immune health and strengthening [17].*
  • The antioxidant effects of Ashwagandha extract are mainly due to the presence of active glycol-withanolides (this is associated with healthy aging effects) [4]. Endogenous damage to mitochondrial DNA by free radicals is believed to be a major contributing factor to aging. Ashwagandha extract may help support healthy aging and support age related health.*
  • Withaferin A, 3-beta-hydroxy-2 and 3-dihydro- withanolide F that is isolated from the Ashwagandha extract has shown promising immune support and healthy homeostatis [5].*
  • More than 50 new withanolides have been found in plants [6]. Several withanolides in Ashwagandha are saponin molecules that possess significant healthy cell growth and reproduction properties. Some of the withanolides with healthy cell growth properties are Withaferin-A, 4β, 20-dihydroxy-i-oxo-5β, 6β,-epoxy-witha-.2, 24-dienolide, withanolide-D, 3-β-hydroxy-2, and 3-dihydro-withanolide [7][8][9][10]. Its healthy cell promoting mechanisms work through diverse pathways and this extract is thought to be most effect for breast cell health [11].*
  • One of the extraordinary effects of this extract is that it selectively promotes the management of unhealthy cells. This proves that it is naturally safe and non-toxic when used at appropriate dosages [12]. A report by Widodo et al., 2007, provided the first molecular evidence about Ashwagandha's selective management of unhealthy cells.*
  • Research has also proven that Ashwagandha is particularly beneficial for joint health. Modern scientific researchers consider this herb a great support for joint mobility and joint health [13]. Patients who received this supplement showed a great improvement with joint relaxation and movement.*
  • A very recent study conducted on Ashwagandha's role in supporting a healthy pain response [14]. Ashwagandha may actively support healthy management of beta-amyloids to further promote brain health [18].*
  • There are reports available that proves the use of Ashwagandha for various immune supporting functions. Research suggests that Ashwagandha extract supplemented in hot milk helps support healthy management of white blood cells. It appears that these plant extracts are capable of supporting a healthy thyroid function [15].*
  • Research also suggests that Ashwagandha supports a healthy heart and liver, which includes healthy management of heart weight and glycogen content as well the healthy separation and flow of blood cells [16].*
  • There is recent scientific research available on this traditionally-used herbal plant as an aphrodisiac for the management of optimal male function [19]. The study suggests its potential role in this capacity and the full-spectrum extract suggests a boost in sperm concentration, ejaculation volume, motile sperm count and an increase in the serum levels of testosterone.*

Nutritional Profile

Ashwagandha is rich in protein, carbohydrate, iron, calcium, carotene and Vitamin C.

The biologically active chemical constituents of this extract contain various pharmaceutical properties due to the presence of alkaloids (isopelletierine, anaferine, cuscohygrine, anahygrine), steroidal lactones (withanolides, withaferins) and saponins like sitoindosides from VII-X. Withaferin-A, acylsterylglucosides, 5-dehydroxy withanolide-R, withasomniferin A, withanine, somniferine, somnine, somniferinine, withananine, pseudo-withanine tropane, pseudo-tropine, and choline are chemical components present.

Suggested Usage / Dosage

The recommended dosage for this extract is 50 mg for up to three times daily.

Ideal Storage Conditions

Use a sealed container to store this product in a cool, dry place. Keep away from direct light and moisture. Once the package is opened, it must be re-sealed and used within 6 months.

Shelf Life

2-years from Date of Manufacture.

References

  1. Teli N. WITHANIA SOMNIFERA (ASHWAGANDHA): A SOURCE OF THERAPEUTIC AGENTS. Vol 1.; 2014.
  2. M.A. Weiner, J. Weiner. Ashwagandha (India ginseng). In: Herbs that Heal. Quantum Books,Mill Valley, CA; 70–72 (1994).
  3. ANTISTRESS ACTIVITY OF ASHWAGANDHA (Withania somnifera Dunal) – A REVIEW Gajarmal Amit Ashok.Review Article International Ayurvedic Medical Journal ISSN:2320 5091 4. Bhattacharya, S.K., Satyan, K.S., Ghosal, S. Antioxidant activity of glycowithanolides.from Withania somnifera . Indian J Exp Biol., 1997; 35(3): 236-239.
  4. Budhiraja, R.D. and Sudhir, S. Review of biological activity of withanolides. JSIR, 1987;.46: 488–491.
  5. Lavie D, Glotter E, Shvo Y. Constituents of Withania somnifera-III.-The side chain of Withaferin A. J Org Chem 1965; 30:17748.
  6. Pabji L, Tyihak E, Palyi V. Cytological effects of compounds.(Withaferin-A and Withferinil) isolated from Withania somnifera. Dun. Herba Hung 1969;8:73.
  7. Chakrabarti SK, Barun DK, Bandyopadhyay P. Variations in the antitumour constituents of Withania somnifera Dunal. Experientia 1974;30:852-3.
  8. Das H, Dultan SK, Bhattacharya B, Chakrabarti SK. Anti-neoplastic agents from plants. Indian J Cancer Chemother 1985;7:59-65
  9. Budhiraja RD, Sudhir S. Review of biological activity of Withenolides (antibacterial, antitumor, immunomodulator, antiinflammatory and insect antifeedcent). J Sci Ind Res 1983;46:488-91
  10. Nema R, Khare S, Jain P, Pradhan A. (2013). Anticancer activity of Withania somnifera (leaves) flavonoides compound. Int J Pharm Sci Rev Res 21:103–6
  11. Selective Killing of Cancer Cells by Leaf Extract of Ashwagandha: Identification of a Tumor-Inhibitory Factor and the First Molecular Insights to Its Effect Nashi Widodo, Kamaljit Kaur, Bhupal G. Shrestha, Yasuomi Tak
  12. Dr. J.L.N.Sastry, Dravyaguna Vijnana, Study of essential Medicinal Plants in Ayurveda Vol 2, Chaukhambha Orientalia,Varanasi.
  13. Contributions to the pharmacodynamic study of roots of Withania somnifera Dun speciesof Pakistani origin. Note III: Testing of analgesic activity of dichlormethanic and methanolicextract from Withania somnifera roots.Sakka Mazen E, Pavelescu M, Grigorescu ERev Med Chir Soc Med Nat Iasi. 1990 Oct-Dec;
  14. J Ethnopharmacol. 1999 Nov 1;67(2):233-9. Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice.Panda S1, Kar A.
  15. Angiogenesis. 2004;7(2):115-22. Withaferin A is a potent inhibitor of angiogenesis. Mohan R1
  16. J Altern Complement Med. 2009 Apr;15(4):423-30. doi: 10.1089/acm.2008.0215. In vivo effects of Ashwagandha (Withania somnifera) extract on the activation of lymphocytes. Mikolai J1.

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