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Biotanica, Premium Bacopa Monnieri Extract

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Biotanica, Premium Bacopa Monnieri Extract

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Boosts Healthy Brain Function.*
Supports Calm Thoughts.*
Contains Antioxidants.*
Promotes Normal Immune Response.*
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Product Description

Bacopa Monnieri is a medicinal herb that is native to India. It is a perennial herb, also called herb of grace, water hyssop, or Brahimi. Bacopa is being used in India Ayurvedic medicine to promote healthy body functions. It is a creeping water-loving plant which grows in wetlands and tropical areas. It was used to improve memory-retention and to enhance brain cell regeneration in people with Alzheimer’s disease [1].

The herb was popular in ancient India due to its ability to aid cognitive abilities. It was used by the Hindus to dedicate new born-babies believing it would make the babies more knowledgeable. Bacopa was first described around 6 AD by some indigenous scholars [2]. The herb can also be found in some parts of Asia and Central America. Though most of these claims are yet to be substantiated by scientific but its potential benefits have attracted scientists’ interest.

Product Benefits

Memory Enhancement

Research suggests that Bacopa aid memory retention and acquisition in geriatric people when given 300mg of the extract for 12 weeks. It was further observed that the herb could improve visual memory. Studies reported that the herb is safe for aiding cognitive ability [3]. The herb is not only safe for use in adults but also in children [2]. It was believed to aid memory retention by supporting cholinergic upregulation and modulation of gamma-aminobutyric acid (GABA). But solid clinical studies to affirm its traditional use is still not convincing [4]. Alcoholic extract of the herb supports cognitive functions.

Calmness & Mood Support

In folk medicine, the herb has been used to promote calming effects in anxious people. The herb has been useful in supporting calming function in people with the anxiety-stress disorder. Research reported that the extract improved calming effect in healthy individuals when it was given for 6 weeks. 450mg of the extract taken daily for 12 weeks has some desirable impact on patients with a psychiatric disorder like anxiety [2]. The herb aids in the proper functioning of the hypothalamus when under stress. Research carried out on rats supported this claim [5]. It is an adaptogenic herb, meaning that it supports the body against stress. It also discourages the production of cortisol (a hormone linked to stress) [9].

Immune Health & Antioxidant Activity

The extract promotes the calming response of cells in the body and brain. Bacopa helps in promoting the mopping up of free radicals; its ability to do this is dose-dependent. The herb aids normal cell response by preventing the release of cytokines. It also ensures normal cell response in patients with rheumatoid arthritis. Its action to promotes normal cell response in rheumatoid arthritis is due to its significant role in inhibiting protein denaturation. It has a 90.34% protein inhibition, which signifies it has a great effect against rheumatoid arthritis. Studies also reported that flavonoid, triterpenoid, and other substances are responsible for its action against arthritis [6]. The herb contains bacoside, a constituent that aids mopping up of free radicals. Lipids react with free radicals through a process called lipid peroxidation. Lipid peroxidation has been implicated in some neurodegenerative diseases like Parkinson's disease, Alzheimer's disease, and others. Research shows that the herb extract can suppress the process, thereby discouraging brain cell degeneration [9].

Healthy Breathing

Histamine has been implicated in causing the allergy. Extract of Bacopa has been reported to stabilize mast cells, thereby reducing the amount of histamine released. In an experiment, the extract was seen to promote bronchodilation in rat studies, thus validating its use as an anti-asthmatic agent in Indian folk medicine. The extract's ability to promote bronchodilation has been traced to its action on the beta-adrenoceptor [8].

Healthy Cell Replication

Cancer is one of the leading causes of death in the world. With the rising cases of cancer worldwide, people have turned to traditional medicine as alternatives. The herb’s extract was noticed to promote healthy replication of cells. Phytosterol has been implicated as the active constituent here. Phytosterols are natural compounds that promote healthy replication of cells. Stigmasterol is the phytosterol isolated from the aerial part of the plant. The herb’s extract was seen to discourage unhealthy replication of unhealthy cells [10]. Another mechanism of action of the extract was found to be apoptosis [11]. The extract may also promote the normal functioning of the heart in patients with high blood pressure.
 
References

1. Stough C, Singh H, Zangara A. Mechanisms, efficacy, and safety of Bacopa monnieri (bacopa) for cognitive and brain enhancement. Evidence Based Complement Alternative Med 2015;2015:717605. Angel lee (2018).

2. History of Bacopa monnieri. [Article] .https://www.entity-health.com/history-of-bacopa-monnieri/ Morgan, A., & Stevens, J. (2010).

3. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. Journal of alternative and complementary medicine (New York, N.Y.), 16(7), 753–759. https://doi.org/10.1089/acm.2009.0342 Calabrese, C., Gregory, W. L., Leo, M., Kraemer, D., Bone, K., & Oken, B. (2008).

4. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. Journal of alternative and complementary medicine (New York, N.Y.), 14(6), 707–713. https://doi.org/10.1089/acm.2008.0018 Rai, D., Bhatia, G., Palit, G., Pal, R., Singh, S., & Singh, H. K. (2003).

5. Adaptogenic effect of Bacopa monniera (Brahmi). Pharmacology, biochemistry, and behavior, 75(4), 823–830. Dar, A., & Channa, S. (1997). Bronchodilatory and cardiovascular effects of an ethanol extract of Bacopa monniera in anaesthetized rats. Phytomedicine : international journal of phytotherapy and phytopharmacology, 4(4), 319–323. https://doi.org/10.1016/S0944-7113(97)80040-2 Ghosh, T., Maity, T.K. & Singh, J.

6. Evaluation of antitumor activity of stigmasterol, a constituent isolated from Bacopa monnieri Linn aerial parts against Ehrlich Ascites Carcinoma in mice. Orient Pharm Exp Med 11, 41–49 (2011). https://doi.org/10.1007/s13596-011-0001-y Ryan R. (october31,2019) .7 benefits of Bacopa monnieri . [Article]. https://www.healthline.com/nutrition/bacopa-monnieri-benefits#section4 Kalyani, M. I., Lingaraju, S. M., & Salimath, B. P. (2013).

6. A pro-apoptotic 15-kDa protein from Bacopa monnieri activates caspase-3 and downregulates Bcl-2 gene expression in mouse mammary carcinoma cells. Journal of natural medicines, 67(1), Kalyani, M. I., Lingaraju, S. M., & Salimath, B. P. (2013).

7. A pro-apoptotic 15-kDa protein from Bacopa monnieri activates caspase-3 and downregulates Bcl-2 gene expression in mouse mammary carcinoma cells. Journal of natural medicines, 67(1), 123–136. https://doi.org/10.1007/s11418-012-0661-z  

Delivery Methods

We ship worldwide using NZ Post Priority and Express Tracked mail service. All orders placed with us are tracked so that you can find your order at any time, once it has been dispatched.

Delivery Time
Most orders are shipped by 4 PM within two business days. If for some reason we cannot ship your order by 4 PM within two business days, we will email you to let you know within 48 hours.

NZ Delivery Time
All New Zealand orders are tracked. Please allow for 2 business days for processing and packaging, with 3 - 5 business days to arrive.

USA Delivery Time
We use tracked Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent

Canada Delivery Time
We use tracked Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent

Australia Delivery Time
We use tracked Priority shipping which may take up to 6 - 8 days. Please allow for 2 business days for processing and packaging before your order is sent.

All Other International Countries Delivery Time
We use Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent.
Returns With Us Are Easy

Biotanica® maintains a total customer satisfaction guarantee on all Biotanica® auto-delivery products. If you, the customer, are unhappy with the product for any reason, you can return the unused item(s) for a full refund of the purchase price minus delivery and handling. To obtain your refund, you must email us at: returns@BiotanicaHealth.com with your order number so we can process your refund.

Your order number can easily be found next to your name on grey package it arrived in.

To receive your refund, your return must be received at our delivery facility within 30 days of purchase. You pay for return delivery.

Please send your package to:

Biotanica® Health
P O Box 147200
Ponsonby
Auckland
1011
New Zealand

We will not accept or issue a refund for any packages marked return to sender or refused. If you return a package, we recommend that you get proof of shipment. Upon receipt of your returned product, a refund will be issued to your credit card.

After the delivery department receives your return, it generally takes 3 - 5 business days or less to process your refund. Once a return is processed, it can take up to one billing cycle for the refund to be posted to your account, depending on your financial banking institution.

Here are 5 more great reasons to buy from us:

You get a full 30 days to return your item to us. If it's not right for you, you've changed your mind or for no reason whatsoever simply send it back to us and we'll cheerfully refund your order less any applicable bank and service fees.

Returns are easy, simply click here for our returns policy. We'll get you a replacement or refund in a snap!

In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down.

We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again.

Ordering from Biotanica® is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone.

Product Description

Bacopa Monnieri is a medicinal herb that is native to India. It is a perennial herb, also called herb of grace, water hyssop, or Brahimi. Bacopa is being used in India Ayurvedic medicine to promote healthy body functions. It is a creeping water-loving plant which grows in wetlands and tropical areas. It was used to improve memory-retention and to enhance brain cell regeneration in people with Alzheimer’s disease [1].

The herb was popular in ancient India due to its ability to aid cognitive abilities. It was used by the Hindus to dedicate new born-babies believing it would make the babies more knowledgeable. Bacopa was first described around 6 AD by some indigenous scholars [2]. The herb can also be found in some parts of Asia and Central America. Though most of these claims are yet to be substantiated by scientific but its potential benefits have attracted scientists’ interest.

Product Benefits

Memory Enhancement

Research suggests that Bacopa aid memory retention and acquisition in geriatric people when given 300mg of the extract for 12 weeks. It was further observed that the herb could improve visual memory. Studies reported that the herb is safe for aiding cognitive ability [3]. The herb is not only safe for use in adults but also in children [2]. It was believed to aid memory retention by supporting cholinergic upregulation and modulation of gamma-aminobutyric acid (GABA). But solid clinical studies to affirm its traditional use is still not convincing [4]. Alcoholic extract of the herb supports cognitive functions.

Calmness & Mood Support

In folk medicine, the herb has been used to promote calming effects in anxious people. The herb has been useful in supporting calming function in people with the anxiety-stress disorder. Research reported that the extract improved calming effect in healthy individuals when it was given for 6 weeks. 450mg of the extract taken daily for 12 weeks has some desirable impact on patients with a psychiatric disorder like anxiety [2]. The herb aids in the proper functioning of the hypothalamus when under stress. Research carried out on rats supported this claim [5]. It is an adaptogenic herb, meaning that it supports the body against stress. It also discourages the production of cortisol (a hormone linked to stress) [9].

Immune Health & Antioxidant Activity

The extract promotes the calming response of cells in the body and brain. Bacopa helps in promoting the mopping up of free radicals; its ability to do this is dose-dependent. The herb aids normal cell response by preventing the release of cytokines. It also ensures normal cell response in patients with rheumatoid arthritis. Its action to promotes normal cell response in rheumatoid arthritis is due to its significant role in inhibiting protein denaturation. It has a 90.34% protein inhibition, which signifies it has a great effect against rheumatoid arthritis. Studies also reported that flavonoid, triterpenoid, and other substances are responsible for its action against arthritis [6]. The herb contains bacoside, a constituent that aids mopping up of free radicals. Lipids react with free radicals through a process called lipid peroxidation. Lipid peroxidation has been implicated in some neurodegenerative diseases like Parkinson's disease, Alzheimer's disease, and others. Research shows that the herb extract can suppress the process, thereby discouraging brain cell degeneration [9].

Healthy Breathing

Histamine has been implicated in causing the allergy. Extract of Bacopa has been reported to stabilize mast cells, thereby reducing the amount of histamine released. In an experiment, the extract was seen to promote bronchodilation in rat studies, thus validating its use as an anti-asthmatic agent in Indian folk medicine. The extract's ability to promote bronchodilation has been traced to its action on the beta-adrenoceptor [8].

Healthy Cell Replication

Cancer is one of the leading causes of death in the world. With the rising cases of cancer worldwide, people have turned to traditional medicine as alternatives. The herb’s extract was noticed to promote healthy replication of cells. Phytosterol has been implicated as the active constituent here. Phytosterols are natural compounds that promote healthy replication of cells. Stigmasterol is the phytosterol isolated from the aerial part of the plant. The herb’s extract was seen to discourage unhealthy replication of unhealthy cells [10]. Another mechanism of action of the extract was found to be apoptosis [11]. The extract may also promote the normal functioning of the heart in patients with high blood pressure.
 
References

1. Stough C, Singh H, Zangara A. Mechanisms, efficacy, and safety of Bacopa monnieri (bacopa) for cognitive and brain enhancement. Evidence Based Complement Alternative Med 2015;2015:717605. Angel lee (2018).

2. History of Bacopa monnieri. [Article] .https://www.entity-health.com/history-of-bacopa-monnieri/ Morgan, A., & Stevens, J. (2010).

3. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. Journal of alternative and complementary medicine (New York, N.Y.), 16(7), 753–759. https://doi.org/10.1089/acm.2009.0342 Calabrese, C., Gregory, W. L., Leo, M., Kraemer, D., Bone, K., & Oken, B. (2008).

4. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. Journal of alternative and complementary medicine (New York, N.Y.), 14(6), 707–713. https://doi.org/10.1089/acm.2008.0018 Rai, D., Bhatia, G., Palit, G., Pal, R., Singh, S., & Singh, H. K. (2003).

5. Adaptogenic effect of Bacopa monniera (Brahmi). Pharmacology, biochemistry, and behavior, 75(4), 823–830. Dar, A., & Channa, S. (1997). Bronchodilatory and cardiovascular effects of an ethanol extract of Bacopa monniera in anaesthetized rats. Phytomedicine : international journal of phytotherapy and phytopharmacology, 4(4), 319–323. https://doi.org/10.1016/S0944-7113(97)80040-2 Ghosh, T., Maity, T.K. & Singh, J.

6. Evaluation of antitumor activity of stigmasterol, a constituent isolated from Bacopa monnieri Linn aerial parts against Ehrlich Ascites Carcinoma in mice. Orient Pharm Exp Med 11, 41–49 (2011). https://doi.org/10.1007/s13596-011-0001-y Ryan R. (october31,2019) .7 benefits of Bacopa monnieri . [Article]. https://www.healthline.com/nutrition/bacopa-monnieri-benefits#section4 Kalyani, M. I., Lingaraju, S. M., & Salimath, B. P. (2013).

6. A pro-apoptotic 15-kDa protein from Bacopa monnieri activates caspase-3 and downregulates Bcl-2 gene expression in mouse mammary carcinoma cells. Journal of natural medicines, 67(1), Kalyani, M. I., Lingaraju, S. M., & Salimath, B. P. (2013).

7. A pro-apoptotic 15-kDa protein from Bacopa monnieri activates caspase-3 and downregulates Bcl-2 gene expression in mouse mammary carcinoma cells. Journal of natural medicines, 67(1), 123–136. https://doi.org/10.1007/s11418-012-0661-z  

Delivery Methods

We ship worldwide using NZ Post Priority and Express Tracked mail service. All orders placed with us are tracked so that you can find your order at any time, once it has been dispatched.

Delivery Time
Most orders are shipped by 4 PM within two business days. If for some reason we cannot ship your order by 4 PM within two business days, we will email you to let you know within 48 hours.

NZ Delivery Time
All New Zealand orders are tracked. Please allow for 2 business days for processing and packaging, with 3 - 5 business days to arrive.

USA Delivery Time
We use tracked Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent

Canada Delivery Time
We use tracked Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent

Australia Delivery Time
We use tracked Priority shipping which may take up to 6 - 8 days. Please allow for 2 business days for processing and packaging before your order is sent.

All Other International Countries Delivery Time
We use Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent.
Returns With Us Are Easy

Biotanica® maintains a total customer satisfaction guarantee on all Biotanica® auto-delivery products. If you, the customer, are unhappy with the product for any reason, you can return the unused item(s) for a full refund of the purchase price minus delivery and handling. To obtain your refund, you must email us at: returns@BiotanicaHealth.com with your order number so we can process your refund.

Your order number can easily be found next to your name on grey package it arrived in.

To receive your refund, your return must be received at our delivery facility within 30 days of purchase. You pay for return delivery.

Please send your package to:

Biotanica® Health
P O Box 147200
Ponsonby
Auckland
1011
New Zealand

We will not accept or issue a refund for any packages marked return to sender or refused. If you return a package, we recommend that you get proof of shipment. Upon receipt of your returned product, a refund will be issued to your credit card.

After the delivery department receives your return, it generally takes 3 - 5 business days or less to process your refund. Once a return is processed, it can take up to one billing cycle for the refund to be posted to your account, depending on your financial banking institution.

Here are 5 more great reasons to buy from us:

You get a full 30 days to return your item to us. If it's not right for you, you've changed your mind or for no reason whatsoever simply send it back to us and we'll cheerfully refund your order less any applicable bank and service fees.

Returns are easy, simply click here for our returns policy. We'll get you a replacement or refund in a snap!

In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down.

We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again.

Ordering from Biotanica® is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone.

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