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D-Mannose Powder

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Supports Urinary Health*
Boosts Liver Function*
Assists Protein Storage*
Healthy Blood Sugar*
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We Care For the Environment

D-Mannose is a type of sugar related to glucose [1]. *

What is D-Mannose?

D-Mannose is found in fruits such as apples, peaches and cranberries. It has also been used for a long time in as a tonic to support a healthy urinary tract as well as a healthy bladder and digestive aid. Both men and women are prone to urinary tract infections. *

How Could D-Mannose Support My Health?

D-Mannose is a stronghold on its own when it comes to the many benefits it offers. We will introduce you to these benefits and the reasoning behind consuming the D-Mannose Powder.
  • Urinary Tract Health. D-Mannose powder is known for its ability to support a healthy urinary tract (UTI) [2]. A series of experiments and research have been conducted to support this. In 2014, a study was conducted on 308 women with various UTIs. They were divided into 3 groups. For 6 months, one group was treated with 2 g of D-Mannose on a daily basis. Another group was given a prescription drug to take and the third group was not treated at all. After 6 months had elapsed, it was discovered that only 14% of the women who had been on D-Mannose had suffered a recurrence of UTIs. In the prescription group, 20% experienced a recurrence and 60% of those who got no treatment at all experienced a recurrence. The conclusion of the study was that this supplement had the ability to support a health urinary tract [2][3]. *
    A majority of UTIs are caused by Escherichia coli (E.coli) [2]. This is a harmless bacteria found in our intestinal tract. However, problems arise when it becomes plentiful in other areas, such as the urinary tract. When the bacteria gets into the urinary tract, it multiplies and leads to symptoms such as a burning sensation when urinating, frequent urges to urinate, lower abdominal pain, blood in the urine and cloudy urine [2]. These symptoms will not always occur at once. The cell walls of the bacteria are covered with tiny projections that are referred to as fimbria. The projections are an adaptive factor that helps the bacteria attach to the inner walls of the bladder [2][3]. With these projections, they can work their way up your bladder to the ureter and kidneys, causing irreversible damage. The projections on the bacteria are comprised of an amino acid-sugar complex (lectin). This causes them to stick and you will not be able to get rid of them through urination.
    It is a good choice to try out D-Mannose to support a healthy urinary tract. *
  • Bladder Health. In addition to supporting a healthy urinary tract, a study has also shown that overall bladder health could be improved immensely with the consumption of D-Mannose [2]. *
  • Digestive Health. D-Mannose has the ability to improve the health of our digestive tract. It may support the digestive tract especially when health complications arise. A study in 2014 analyzed the relationship between glyconutrients and illnesses in patients suffering from duodenal ulcers and gastric cancer. Patients suffering from gastric cancer were found to have reduced levels of mannose glycans [5]. This was similar to the patients with duodenal ulcers. *
    Evidence from in vitro and animal studies also shows that D-Mannose plays a great role in fighting against the effects of lectins [5]. Lectins are a type of protein found in certain legumes and vegetables. Most of the foods we currently consume have this protein. The worst part is that the protein does not degrade in our stomach acid and digesting them is an extremely difficult task. To curb the accumulation of lectins, D-Mannose acts as a decoy molecule for the protein [4][5]. It is then able to bind to the compounds that would normally bind to the mannose sugar of our body cells. This mechanism protects our body cells from lectin-related reactions. *

Suggested Usage / Dosage

The recommended dosage of D-Mannose varies from person to person due to individual reasons for taking it. However, we recommend a dosage of 1,500 mg per day for general bladder health or 500 mg every 3 hours for urinary tract health. *

Ideal Storage Conditions

Use a sealed container to store this product in a cool, dry place. Keep away from direct light and moisture. Once the package is opened, it must be re-sealed and used within 6 months.

Shelf Life

2-years from Date of Manufacture.

References

  1. Albersheim, P., Nevins, D. J., English, P. D., & Karr, A. (1967). A method for the analysis of sugars in plant cell-wall polysaccharides by gas-liquid chromatography. Carbohydrate Research, 5(3), 340-345.
  2. Hull, R. A., Gill, R. E., Hsu, P. A. T. R. I. C. I. A., Minshew, B. H., & Falkow, S. T. A. N. L. E. Y. (1981). Construction and expression of recombinant plasmids encoding type 1 or D-mannose-resistant pili from a urinary tract infection Escherichia coli isolate. Infection and Immunity, 33(3), 933-938.
  3. Hung, C. S., Bouckaert, J., Hung, D., Pinkner, J., Widberg, C., DeFusco, A., ... & Hultgren, S. J. (2002). Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Molecular microbiology, 44(4), 903-915.
  4. Wright, E. M., Hirayama, B. A., & Loo, D. F. (2007). Active sugar transport in health and disease. Journal of internal medicine, 261(1), 32-43.
  5. Newman, K. (1994). Mannan-oligosaccharides: Natural polymers with significant impact on the gastrointestinal microflora and the immune system. Biotechnology in the feed industry, 10, 167-174.

   
Delivery Methods

We ship worldwide using NZ Post Priority and Express Tracked mail service. All orders placed with us are tracked so that you can find your order at any time, once it has been dispatched.

Delivery Time
Most orders are shipped by 4 PM within two business days. If for some reason we cannot ship your order by 4 PM within two business days, we will email you to let you know within 48 hours.

NZ Delivery Time
All New Zealand orders are tracked. Please allow for 2 business days for processing and packaging, with 3 - 5 business days to arrive.

USA Delivery Time
We use tracked Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent

Canada Delivery Time
We use tracked Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent

Australia Delivery Time
We use tracked Priority shipping which may take up to 6 - 8 days. Please allow for 2 business days for processing and packaging before your order is sent.

All Other International Countries Delivery Time
We use Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent.
Returns With Us Are Easy

Biotanica® maintains a total customer satisfaction guarantee on all Biotanica® auto-delivery products. If you, the customer, are unhappy with the product for any reason, you can return the unused item(s) for a full refund of the purchase price minus delivery and handling. To obtain your refund, you must email us at: returns@BiotanicaHealth.com with your order number so we can process your refund.

Your order number can easily be found next to your name on grey package it arrived in.

To receive your refund, your return must be received at our delivery facility within 30 days of purchase. You pay for return delivery.

Please send your package to:

Biotanica® Health
P O Box 147200
Ponsonby
Auckland
1011
New Zealand

We will not accept or issue a refund for any packages marked return to sender or refused. If you return a package, we recommend that you get proof of shipment. Upon receipt of your returned product, a refund will be issued to your credit card.

After the delivery department receives your return, it generally takes 3 - 5 business days or less to process your refund. Once a return is processed, it can take up to one billing cycle for the refund to be posted to your account, depending on your financial banking institution.

Here are 5 more great reasons to buy from us:

   

You get a full 30 days to return your item to us. If it's not right for you, you've changed your mind or for no reason whatsoever simply send it back to us and we'll cheerfully refund your order less any applicable bank and service fees.

Returns are easy, simply click here for our returns policy. We'll get you a replacement or refund in a snap!

In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down.

We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again.

Ordering from Biotanica® is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone.

D-Mannose is a type of sugar related to glucose [1]. *

What is D-Mannose?

D-Mannose is found in fruits such as apples, peaches and cranberries. It has also been used for a long time in as a tonic to support a healthy urinary tract as well as a healthy bladder and digestive aid. Both men and women are prone to urinary tract infections. *

How Could D-Mannose Support My Health?

D-Mannose is a stronghold on its own when it comes to the many benefits it offers. We will introduce you to these benefits and the reasoning behind consuming the D-Mannose Powder.
  • Urinary Tract Health. D-Mannose powder is known for its ability to support a healthy urinary tract (UTI) [2]. A series of experiments and research have been conducted to support this. In 2014, a study was conducted on 308 women with various UTIs. They were divided into 3 groups. For 6 months, one group was treated with 2 g of D-Mannose on a daily basis. Another group was given a prescription drug to take and the third group was not treated at all. After 6 months had elapsed, it was discovered that only 14% of the women who had been on D-Mannose had suffered a recurrence of UTIs. In the prescription group, 20% experienced a recurrence and 60% of those who got no treatment at all experienced a recurrence. The conclusion of the study was that this supplement had the ability to support a health urinary tract [2][3]. *
    A majority of UTIs are caused by Escherichia coli (E.coli) [2]. This is a harmless bacteria found in our intestinal tract. However, problems arise when it becomes plentiful in other areas, such as the urinary tract. When the bacteria gets into the urinary tract, it multiplies and leads to symptoms such as a burning sensation when urinating, frequent urges to urinate, lower abdominal pain, blood in the urine and cloudy urine [2]. These symptoms will not always occur at once. The cell walls of the bacteria are covered with tiny projections that are referred to as fimbria. The projections are an adaptive factor that helps the bacteria attach to the inner walls of the bladder [2][3]. With these projections, they can work their way up your bladder to the ureter and kidneys, causing irreversible damage. The projections on the bacteria are comprised of an amino acid-sugar complex (lectin). This causes them to stick and you will not be able to get rid of them through urination.
    It is a good choice to try out D-Mannose to support a healthy urinary tract. *
  • Bladder Health. In addition to supporting a healthy urinary tract, a study has also shown that overall bladder health could be improved immensely with the consumption of D-Mannose [2]. *
  • Digestive Health. D-Mannose has the ability to improve the health of our digestive tract. It may support the digestive tract especially when health complications arise. A study in 2014 analyzed the relationship between glyconutrients and illnesses in patients suffering from duodenal ulcers and gastric cancer. Patients suffering from gastric cancer were found to have reduced levels of mannose glycans [5]. This was similar to the patients with duodenal ulcers. *
    Evidence from in vitro and animal studies also shows that D-Mannose plays a great role in fighting against the effects of lectins [5]. Lectins are a type of protein found in certain legumes and vegetables. Most of the foods we currently consume have this protein. The worst part is that the protein does not degrade in our stomach acid and digesting them is an extremely difficult task. To curb the accumulation of lectins, D-Mannose acts as a decoy molecule for the protein [4][5]. It is then able to bind to the compounds that would normally bind to the mannose sugar of our body cells. This mechanism protects our body cells from lectin-related reactions. *

Suggested Usage / Dosage

The recommended dosage of D-Mannose varies from person to person due to individual reasons for taking it. However, we recommend a dosage of 1,500 mg per day for general bladder health or 500 mg every 3 hours for urinary tract health. *

Ideal Storage Conditions

Use a sealed container to store this product in a cool, dry place. Keep away from direct light and moisture. Once the package is opened, it must be re-sealed and used within 6 months.

Shelf Life

2-years from Date of Manufacture.

References

  1. Albersheim, P., Nevins, D. J., English, P. D., & Karr, A. (1967). A method for the analysis of sugars in plant cell-wall polysaccharides by gas-liquid chromatography. Carbohydrate Research, 5(3), 340-345.
  2. Hull, R. A., Gill, R. E., Hsu, P. A. T. R. I. C. I. A., Minshew, B. H., & Falkow, S. T. A. N. L. E. Y. (1981). Construction and expression of recombinant plasmids encoding type 1 or D-mannose-resistant pili from a urinary tract infection Escherichia coli isolate. Infection and Immunity, 33(3), 933-938.
  3. Hung, C. S., Bouckaert, J., Hung, D., Pinkner, J., Widberg, C., DeFusco, A., ... & Hultgren, S. J. (2002). Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Molecular microbiology, 44(4), 903-915.
  4. Wright, E. M., Hirayama, B. A., & Loo, D. F. (2007). Active sugar transport in health and disease. Journal of internal medicine, 261(1), 32-43.
  5. Newman, K. (1994). Mannan-oligosaccharides: Natural polymers with significant impact on the gastrointestinal microflora and the immune system. Biotechnology in the feed industry, 10, 167-174.

   
Delivery Methods

We ship worldwide using NZ Post Priority and Express Tracked mail service. All orders placed with us are tracked so that you can find your order at any time, once it has been dispatched.

Delivery Time
Most orders are shipped by 4 PM within two business days. If for some reason we cannot ship your order by 4 PM within two business days, we will email you to let you know within 48 hours.

NZ Delivery Time
All New Zealand orders are tracked. Please allow for 2 business days for processing and packaging, with 3 - 5 business days to arrive.

USA Delivery Time
We use tracked Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent

Canada Delivery Time
We use tracked Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent

Australia Delivery Time
We use tracked Priority shipping which may take up to 6 - 8 days. Please allow for 2 business days for processing and packaging before your order is sent.

All Other International Countries Delivery Time
We use Priority shipping which may take up to 8 - 12 days. For Express Orders please allow for 4 - 6 days for delivery. Please allow for 2 business days for processing and packaging before your order is sent.
Returns With Us Are Easy

Biotanica® maintains a total customer satisfaction guarantee on all Biotanica® auto-delivery products. If you, the customer, are unhappy with the product for any reason, you can return the unused item(s) for a full refund of the purchase price minus delivery and handling. To obtain your refund, you must email us at: returns@BiotanicaHealth.com with your order number so we can process your refund.

Your order number can easily be found next to your name on grey package it arrived in.

To receive your refund, your return must be received at our delivery facility within 30 days of purchase. You pay for return delivery.

Please send your package to:

Biotanica® Health
P O Box 147200
Ponsonby
Auckland
1011
New Zealand

We will not accept or issue a refund for any packages marked return to sender or refused. If you return a package, we recommend that you get proof of shipment. Upon receipt of your returned product, a refund will be issued to your credit card.

After the delivery department receives your return, it generally takes 3 - 5 business days or less to process your refund. Once a return is processed, it can take up to one billing cycle for the refund to be posted to your account, depending on your financial banking institution.

Here are 5 more great reasons to buy from us:

   

You get a full 30 days to return your item to us. If it's not right for you, you've changed your mind or for no reason whatsoever simply send it back to us and we'll cheerfully refund your order less any applicable bank and service fees.

Returns are easy, simply click here for our returns policy. We'll get you a replacement or refund in a snap!

In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down.

We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again.

Ordering from Biotanica® is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone.

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