What is Eucalyptus Oil?

How Could Eucalyptus Essential Oil Improve My Health?

• Eucalyptus Oil presents a broad range of health benefits. It exerts positive effects for cold and respiratory health, and healthy microbial management.*
• Eucalyptus Oil contains numerous flavanones that are structurally related to pinocembrin and it is present in abundant amounts. Methylated flavonoids contain therapeutic properties that help to improve intestinal absorption, enhance bioactivities, and increase metabolic stability [2]. Pinocembrin exhibits properties that may make it effective for supporting cardiovascular health and cell homeostasis [3]. They have the ability to reduce reactive oxygen species and healthy flammation, and also presents with neuroprotective effects such as supporting brain health and brain recovery [4]. Pinocembrin is readily absorbed following oral administration and is capable of passing through the blood-brain barrier in a passive transport process [5].*
• The strong antimicrobial activity of Eucalyptus Oil may be directly associated with their major compounds such as 1,8-cineole and α-pinene or alternatively with the synergy between major and minor constituents [8]. Many studies have reported on viral support activities of Eucalyptus Oil [6][7]. Enteroviruses are more prevalent in the environment. [8]. Eucalyptus Oils have shown strong bacterial supporting activity [8]. Eucalyptus Oil was tested against five fungal strains that included one opportunist pathogenic yeast (Candida albicans), one filamentous (Scopulariopsis brevicaulis) and three dermatophytes (Trichophyton rubrum, Trichophyton soudanense, and Microsporum canis). All tested fungal and yeast strains were more sensitive to Eucalyptus Oil [8]. Eucalyptus Oil also has an effect on the monocytic/macrophagic system, i.e. one of the primary cellular effectors of the immune response against homeostasis [16]. It can induce the activation of innate cell-mediated immune responses and intensely stimulate their phagocytic responses, which can be helpful for respiratory health.*
• The effects of essential oils from the Eucalyptus plant on melanogenesis and the oil's antioxidant characteristics were investigated [9]. In pharmaceutical and dermatological fields, antioxidants have been widely used to prevent or treat disorders related to oxidative stress. Results indicated that Eucalyptus Oil significantly inhibits tyrosinase activity, decreases melanin synthesis and exhibited exceptional intracellular free radical scavenging, proving its worthiness as a promising antioxidant [9]. Due to promising results, it is been used in the cosmetic industry to promote skin health.*
• Eucalyptus Oil has had outstanding positive effects on human gastrointestinal health. More than 50% of the world's population is infected with Helicobacter pylori in their upper gastrointestinal tract. Infection is more common in developing countries compared to Western countries. The in vitro gastro supporting properties of the Eucalyptus plant was investigated in six strains. The anti-H. pylori property demonstrated by Eucalyptus extracts may be attributed to their chemical constituents. It can also explain their reported traditional use, as well as their gastro-protective properties as demonstrated on experimental animals [10]. The stomach health effects of methanol extracts of the Eucalyptus plant was investigated in acetic acid-induced ulcers in rats. Results showed that Eucalyptus extracts support healthy cell growth at day 5. At the end of the fourteenth day, optimal stomach health was noted [11]. From this, a new triterpenoid compound (eucalyptanoic acid) was isolated from the fresh uncrushed leaves of the Eucalyptus plant. This compound was discovered to be the most active spasmolytic health agent. Its effect was mediated through a blockade of calcium influx at 1 mg/ml [12].*
• The anti-proliferative effects of 1, 8-cineole was studied on human colon cell line health. Eucalyptus Oil was characterized by a very high concentration of 1, 8-cineole. The results indicated that 1, 8-cineole suppressed human colorectal health proliferation by inducing apoptosis. Based on these studies, 1, 8-cineole would be an effective way to support colorectal health [13]. It also supported the health management of cell mass, with a promising effect against WEHI-3 cells, and it exhibited a low cytotoxic effect [14]. There are studies available on Eucalyptus Oil that show its potent cytotoxic effects and supports liver and lung cell line health [14][15].*
• Acetaminophen administration causes kidney damage. Eucalyptus Oil can provide beneficial effects on Kidney Health. The localization of flavonoids in membrane interiors and their resulting restrictions on the fluidity of membrane components could strictly hinder the diffusion of free radicals generated during acetaminophen oxidation, thereby decreasing further health [16]. Eucalyptus Oil exerts an in vivo antioxidant effect against reactive oxygen species generated following acetaminophen oxidation and could support Kidney Health [17].*
• The blood glucose supporting effects of the ethanolic extract of Eucalyptus camaldulensis leaves were studied with an oral glucose tolerance test on albino rats. The administration of the ethanolic extract at a dose of 500 mg/kg of body weight showed a highly significant blood glucose supporting agent when compared with a control group [18].*
• Healthy parasite support has also been attributed to Eucalyptus.*

Nutritional Value or Phytochemical Content

Suggested Usage / Dosage

Ideal Storage Conditions

Use a sealed container to store this product in a cool, dry place. Keep away from direct light and moisture. Once the package is opened, it must be re-sealed and used within 6 months.

Shelf Life

2 years from Date of Manufacture.

References

1. Boukef MK. Médicine traditionnelle et pharmacopée, les plantes dans la médicine traditionnelle tunisienne. Agence de Coopération Culturelle et Technique. 1986;92-:9028–085-9
2. Goodger, Jason Q. D. et al. “Foliar Essential Oil Glands of Eucalyptus Subgenus Eucalyptus (Myrtaceae) Are a Rich Source of Flavonoids and Related Non-Volatile Constituents.” Ed. Björn Hamberger. PLoS ONE 11.3 (2016): e0151432. PMC. Web. 23 Jan. 2018.
3. Pinocembrin: a novel natural compound with versatile pharmacological and biological activities.Rasul A, Millimouno FM, Ali Eltayb W, Ali M, Li J, Li X Biomed Res Int. 2013; 2013():379850.
4. The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications. Lan X, Wang W, Li Q, Wang J Mol Neurobiol. 2016 Apr; 53(3):1794-1801.
5. Uptake characteristics of pinocembrin and its effect on p-glycoprotein at the blood-brain barrier in in vitro cell experiments. Yang ZH, Sun X, Qi Y, Mei C, Sun XB, Du GH J Asian Nat Prod Res. 2012; 14(1):14-21.
6. Effect of eucalyptus essential oil on respiratory bacteria and viruses. Cermelli C, Fabio A, Fabio G, Quaglio P Curr Microbiol. 2008 Jan; 56(1):89-92.
7. Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture. Schnitzler P, Schön K, Reichling J Pharmazie. 2001 Apr; 56(4):343-7.
8. Elaissi, Ameur et al. “Chemical Composition of 8 eucalyptus Species’ Essential Oils and the Evaluation of Their Antibacterial, Antifungal and Antiviral Activities.” BMC Complementary and Alternative Medicine 12 (2012): 81. PMC. Web. 23 Jan. 2018.
9. Huang, Huey-Chun et al. “Investigation of the Anti-Melanogenic and Antioxidant Characteristics of Eucalyptus Camaldulensis Flower Essential Oil and Determination of Its Chemical Composition.” Ed. Alejandro Cifuentes. International Journal of Molecular Sciences 16.5 (2015): 10470–10490. PMC. Web. 23 Jan. 2018.
10. Adeniyi, Christiana Bola A., Temitope Olufunmilayo Lawal, and Gail B. Mahady. “In Vitro Susceptibility of Helicobacter Pylori to Extracts of Eucalyptus Camaldulensis and Eucalyptus Torelliana.” Pharmaceutical biology 47.1 (2009): 99–102. Print.
11. Lawal TO, Adeniyi BA and Olaleye SB. Ulcer-healing promoting activities of methanol extracts of Eucalyptus camaldulensis Dehnh. and Eucalyptus torelliana F. Muell in rat. A rch Bas App Med 2014; 2: 147 -152.
12. Begum S ,Sultana I, Siddiqui BS , Shaheen F and Gilani AH. Structure and apasmolytic activity of eucalyptanoic acid from Eucalyptus camaldulensis var. obtusa and synthesis of its active derivative from oleanolic acid. J Nat Prod 2002; 65 (12): 1939–1941.
13. Murata S, Shiragami R, Kosugi C et al. Antitumor effect of 1, 8-cineole against colon cancer. Onchology Report 2013: 2647-2652.
14. Mubarak EE, Zeenelabdin Ali L, Ahmed IFA, Ahmed ABA and Taha RM. Essential oil compositions and cytotoxicity from various organs of Eucalyptus camaldulensis. Int J Agric Biol 2015; 17: 320‒326.
15. El-Baz FK, Mahmoud Kh, El-Hallouty SM, El-Kinawy OS and Ali SI. Antioxidant, antiproliferated activities and GC/MS analysis of Eucalyptus camaldulensis essential oil. Int J Pharm Bio Sci 2015; 6(2):(B) 883 – 892.
16. The localization of flavonoids in the membrane interiors and their resulting restrictions on the fluidity of membrane components could strictly hinder the diffusion of free radicals generated during acetaminophen oxidation, and there by decrease resulting damage effects
17. Dhibi, Sabah et al. “Eucalyptus Globulus Extract Protects upon Acetaminophen-Induced Kidney Damages in Male Rat.” Bosnian Journal of Basic Medical Sciences 14.2 (2014): 99–104. Print. 18. Dawoud ADH. Effects of ethanolic leaf extract of Eucalyptus camaldulensis on oral glucose tolerance test in type-2 model diabetic rats. Journal of Network Communications and Emerging Technologies (JNCET) 2015; 2(2): 6-8
18. El-Baz FK, Mahmoud K, El-Senousy WM, Darwesh OM and ElGohary AE. Antiviral – antimicrobial and schistosomicidal activities of Eucalyptus camaldulensis essential oils. Int J Pharm Sci Rev Res 2015; 31(1): 262-268.
19. Nosratabadi SJ, Sharifi I, Sharififar F, Bamorovat M, Daneshvar H and Mirzaie M. In vitro antileishmanial activity of methanolic and aqueous extracts of Eucalyptus camaldulensis against Leishmania major. J Parasit Dis 2015; 39(1): 18-21.
20. Kabiru YA, Ogbadoyi EO, Okogun JI, Gbodi TA and Makun HA. Anti-trypanosomal potential of Eucalyptus camaldulensis. British Journal of Pharmacology and Toxicology 2013; 4(2): 25-32.
21. Hassani S, Asghari G, Yousefi H, Kazemian A, Rafieiean M and Darani HY. Effects of different extracts of Eucalyptus camaldulensis on Trichomonas vaginalis parasite in culture medium. Adv Biomed Res 2013; 2: 47.